Endocrine Abstracts

Previous studies demonstrate unexpectly high human fat cell turnover. About 10% of the total peripheral fat cell pool is renewed every year. In relative terms this turnover is two-fold increased in obesity but reduced in subjects with pernicious adipose morphology (few but large fat cells). High turnover necessitates a renewable source of adipocyte precursors. Two independent studies, using bone marrow transplanted patients as model, demonstrated important contribution of bone...